Job Description
We are seeking a highly motivated scientist/scientific associate to join our in vivo Cancer Pharmacology and Cancer Translational Research team at China Novartis Institute for Biomedical Research (CNIBR) located in the newly completed state-of-art campus in Zhangjiang, Pudong, Shanghai. The scientist/scientific associate will lead/perform in vivo studies in the characterization and development of novel anti-cancer agents, including both small molecules and biologics. The person will interact with in vitro biology, medicinal chemistry, DMPK and bioinformatics teams to advance oncology agents through the R&D pipeline.

Key responsibilities include:
?Establish and characterize animal tumor models
?Conduct in vivo pharmacology studies to evaluate MTD, PK/PD correlation and efficacy of novel therapeutic agents, as well as investigate their mechanism of action in animal tumor models
?Analyze the results and present research findings to project teams
?keep up-to-date with the literature related to the projects
?Effectively collaborate with multi-disciplinary teams
?Manage out-sourcing projects when needed
?Highly value and fully follow IACUC, IP, ISEC and HSE policies

Qualifications:
?A MS degree with 3+ years of experience, or a BS degree with 5+ years of experience in in vivo cancer pharmacology
?Industrial working experiences, especially the experiences in leading in vivo cancer pharmacology studies is preferred
?Solid hands-on skills in cell culture, cell/tumor implantation, drug administration and tissue sampling
?Expertise in in vivo bioluminescence imaging technique and X-ray irradiator is a plus.
?Experience in development or validation of an animal clinical scoring system is a plus.
?Skilled at small animal surgery is a plus.
?Experience in novel in vivo techniques is a plus.
?Detail-oriented, with excellent organizational and record-keeping skills
?Demonstrate a high level of initiative in troubleshooting experiments
?Capable of working both independently and as part of multidisciplinary teams
?Great communication and presentation skills
?Working proficiency in English

作為諾華全球藥物研發(fā)網(wǎng)絡(luò)的一部分，諾華（中國）生物醫(yī)學(xué)研究中心（CNIBR）于2007 年正式投入運(yùn)營(yíng)，成為跨國醫(yī)藥健康企業(yè)在華建立的首家、也是規(guī)模最大的綜合性研發(fā)中心。通過多年發(fā)展，研發(fā)中心成為諾華生物醫(yī)學(xué)研究中心（NIBR）在亞太地區(qū)的重要基地，依托自身在新藥研發(fā)領(lǐng)域的強(qiáng)大實(shí)力，通過各種形式的合作與交流惠及包括韓國、日本、臺(tái)灣在內(nèi)的多個(gè)國家和地區(qū)的醫(yī)藥研發(fā)。研發(fā)中心扎根上海，旨在通過與本土生命科學(xué)研究機(jī)構(gòu)廣泛開展合作，引領(lǐng)區(qū)域性創(chuàng)新新藥研發(fā)。